The reaction between cyanide and the mixed disulphide of cysteine and penicillamine.
نویسنده
چکیده
منابع مشابه
Evaluation of Oxidative Stress in Combination Therapy with D-penicillamine and N-Acetylcysteine (NAC) in Lead Poisoning in Opium Addicts
Background: N-acetylcysteine (NAC) is a putative antioxidant and has gained attention as a promising agent for chelating heavy metals including lead. Considering the animal studies results, we hypothesized that adding NAC to the treatment regimen may improve the success of treatment with lead chelators. Methods: A total of 46 patients who were lead-poisoned opioid addicts were divided into two ...
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The enzyme rhodanese (thiosulfate: cyanide sulfurtransferase) is a ubiquitous enzyme and its activity ispresent in all living organisms. Many functions including cyanide detoxification, formation of iron-sulfurcenters and participation in energy metabolism have been attributed to this enzyme. The enzyme catalyzesthe transfer of a sulfur atom from sulfane containing compounds (such as thiosulfat...
متن کاملPre-concentration of Penicillamine using Fe3O4NPS and analysis of it in drug formulations through spectroscopic method
First, an effective pre-concentration of penicillamine was done via Fe3O4NPS. Then, a simple, rapid and sensitive spectrophotometric method is described for the determination of penicillamine by 2, 6-dichlorophenolindophenol (2, 6-DCPIP), as the chromogenic agent in bulk drug and formulations. It produces a bluish green coloured compound with maximum absorbance 610 nm. Bee...
متن کاملPre-concentration of Penicillamine using Fe3O4NPS and analysis of it in drug formulations through spectroscopic method
First, an effective pre-concentration of penicillamine was done via Fe3O4NPS. Then, a simple, rapid and sensitive spectrophotometric method is described for the determination of penicillamine by 2, 6-dichlorophenolindophenol (2, 6-DCPIP), as the chromogenic agent in bulk drug and formulations. It produces a bluish green coloured compound with maximum absorbance 610 nm. Bee...
متن کاملLactoperoxidase catalyzes in vitro activation of acrylonitrile to cyanide.
Acrylonitrile (ACN) is a widely used industrial chemical. Although it is a well reported animal carcinogen, its current designation to humans is "possibly carcinogenic". The present study aimed at investigating the ability of LPO enzyme system to oxidize ACN to cyanide (CN(-)) in vitro. Detection of CN(-) served as a marker for the possible generation of free radical intermediates implicated in...
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عنوان ژورنال:
- Journal of the Chemical Society. Perkin transactions 1
دوره 22 شماره
صفحات -
تاریخ انتشار 1968